Medicinal properties of alpha-santalol, a naturally occurring constituent of sandalwood oil: review

被引：43

作者：

Bommareddy, Ajay ^{[1
]}

Brozena, Sarah ^{[1
]}

Steigerwalt, James ^{[1
]}

Landis, Terra ^{[1
]}

Hughes, Sarah ^{[1
]}

Mabry, Erica ^{[1
]}

Knopp, Aaron ^{[1
]}

VanWert, Adam L. ^{[1
]}

Dwivedi, Chandradhar ^{[2
]}

机构：

[1] Wilkes Univ, Nesbitt Sch Pharm, Dept Pharmaceut Sci, Wilkes Barre, PA 18766 USA

[2] South Dakota State Univ, Coll Pharm, Dept Pharmaceut Sci, Brookings, SD 57007 USA

来源：

NATURAL PRODUCT RESEARCH | 2019年 / 33卷 / 04期

关键词：

Alpha-santalol; apoptosis; diabetes; cancer; inflammation; SKIN TUMOR-DEVELOPMENT; CANCER CHEMOPREVENTIVE AGENT; EAST-INDIAN SANDALWOOD; BREAST-CANCER; ACID; RADIATION; CELLS; DEATH; ALBUM; CD-1;

D O I：

10.1080/14786419.2017.1399387

中图分类号：

O69 [应用化学];

学科分类号：

070301 [无机化学];

摘要：

Alpha-santalol is a naturally occurring sesquiterpene that is derived from sandalwood oil. Its wide range of health benefits have been attributed to the modulation of various signalling pathways involved in the development of a particular disease. For example, the antitumour and cancer preventive properties of alpha-santalol have been shown to involve cell death induction through apoptosis and cell cycle arrest in various cancer models. A marked decrease in inflammatory markers have also been shown with alpha-santalol administration in skin tissue models. The current review is aimed at bringing the most recent advances of alpha-santalol against various disease-specific models and highlighting its associated mechanistic details. [GRAPHICS] .

引用

页码：527 / 543

页数：17

共 38 条

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[3]

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