Heightened Neurologic Complications in Children with Pandemic H1N1 Influenza

被引:78
作者
Ekstrand, Jeffrey J. [1 ]
Herbener, Amy [2 ]
Rawlings, Julia [3 ]
Turney, Beth [4 ]
Ampofo, Krow [2 ]
Korgenski, E. Kent [5 ]
Bonkowsky, Joshua L. [1 ]
机构
[1] Univ Utah, Sch Med, Div Pediat Neurol, Salt Lake City, UT USA
[2] Univ Utah, Sch Med, Div Pediat Infect Dis, Salt Lake City, UT USA
[3] Univ Utah, Sch Med, Dept Pediat, Salt Lake City, UT USA
[4] Univ N Carolina, Dept Pediat, Chapel Hill, NC USA
[5] Intermt Hlth Care, Salt Lake City, UT USA
关键词
A H1N1; INFECTION; VIRUS; HOSPITALIZATION; ENCEPHALOPATHY; TEXAS;
D O I
10.1002/ana.22184
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The 2009 pandemic influenza A (H1N1) has been recognized to cause neurological complications including seizures and encephalopathy. We identified 18 children with 2009 H1N1 influenza and neurological complications from first and second wave activity, and compared characteristics to seasonal influenza. Seizures, encephalopathy, and status epilepticus were common presentations. Focal neurological symptoms persisted in 22% of patients at discharge. Compared to seasonal influenza, patients with pandemic 2009 influenza were more likely to have encephalopathy, focal neurological findings, aphasia, and abnormal electroencephalographic findings. In addition, we noted a trend toward heightened neurological complications following second wave influenza activity. ANN NEUROL 2010;68:762-766
引用
收藏
页码:762 / 766
页数:5
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