Pulmonary actinomycosis complicating infliximab therapy for Crohn's disease

被引:23
作者
Cohen, R. D. [1 ]
Bowie, W. R.
Enns, R.
Flint, J.
Fitzgerald, J. M.
机构
[1] Univ British Columbia, Dept Med, Vancouver, BC, Canada
[2] Univ British Columbia, Dept Pathol, Vancouver, BC, Canada
关键词
D O I
10.1136/thx.2006.075150
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
The use of anti-tumour necrosis factor (TNF) agents has expanded significantly over the past few years, particularly for rheumatologtcal diseases and Crohn's disease. A number of associated opportunistic infections have been observed as a result of suppression of T cell-mediated immunity, the most frequent being tuberculosis. We report the first case of pulmonary actinomycosis in a patient receiving regular infusions of infliximab, an anti-TNF agent, for Crohn's disease.
引用
收藏
页码:1013 / 1014
页数:2
相关论文
共 13 条
[1]   ENDOBRONCHIAL ACTINOMYCOSIS SIMULATING BRONCHOGENIC-CARCINOMA - DIAGNOSIS BY BRONCHIAL BIOPSY [J].
ARIEL, I ;
BREUER, R ;
KAMAL, NS ;
BENDOV, I ;
MOGLE, P ;
ROSENMANN, E .
CHEST, 1991, 99 (02) :493-495
[2]   Tumor necrosis factor α antibody (infliximab) therapy profoundly down-regulates the inflammation in Crohn's ileocolitis [J].
Baert, FJ ;
D'Haens, GR ;
Peeters, M ;
Hiele, MI ;
Schaible, TF ;
Shealy, D ;
Geboes, K ;
Rutgeerts, PJ .
GASTROENTEROLOGY, 1999, 116 (01) :22-28
[3]   Actinomyces odontolyticus thoracopulmonary infections - Two cases in lung and heart-lung transplant recipients and a review of the literature [J].
Bassiri, AG ;
Girgis, RE ;
Theodore, J .
CHEST, 1996, 109 (04) :1109-1111
[4]  
Bell SJ, 2000, ALIMENT PHARM THER, V14, P501
[5]   Complications of biological therapy for inflammatory bowel diseases [J].
Blonski, W ;
Lichtenstein, GR .
CURRENT OPINION IN GASTROENTEROLOGY, 2006, 22 (01) :30-43
[6]   PULMONARY ACTINOMYCOSIS - A CAUSE OF ENDOBRONCHIAL DISEASE IN A PATIENT WITH AIDS [J].
CENDAN, I ;
KLAPHOLZ, A ;
TALAVERA, W .
CHEST, 1993, 103 (06) :1886-1887
[7]   Lung, pleural and colon actinomycosis in an immunocompromised patient: A rare form of presentation [J].
Charalabopoulos, K ;
Charalabopoulos, AK ;
Papalimneou, V ;
Ioachim, E ;
Constantopoulos, SH .
CHEMOTHERAPY, 2003, 49 (04) :209-211
[8]   Infections associated with tumor necrosis factor-α antagonists [J].
Crum, NF ;
Lederman, ER ;
Wallace, MR .
MEDICINE, 2005, 84 (05) :291-302
[9]  
FISHER MS, 1980, J CAN ASSOC RADIOL, V31, P149
[10]   Infliximab induction and maintenance therapy for moderate-to-severe psoriasis: a phase III, multicentre, double-blind trial [J].
Reich, K ;
Nestle, FO ;
Papp, K ;
Ortonne, JP ;
Evans, R ;
Guzzo, C ;
Li, S ;
Dooley, LT ;
Griffiths, CEM .
LANCET, 2005, 366 (9494) :1367-1374