Rv2358 and FurB:: Two transcriptional regulators from Mycobacterium tuberculosis which respond to zincl

被引：37

作者：

Canneva, F

Branzoni, M

Riccardi, G

Provvedi, R

Milano, A

机构：

[1] Univ Pavia, Dipartimento Genet & Microbiol, I-27100 Pavia, Italy

[2] Univ Padua, Dipartimento Istol Microbiol & Biotecnol Med, Padua, Italy

来源：

JOURNAL OF BACTERIOLOGY | 2005年 / 187卷 / 16期

关键词：

D O I：

10.1128/JB.187.16.5837-5840.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In a previous work, we demonstrated that the Mycobacterium tuberculosis Rv2358-furB operon is induced by zinc. In this study, the orthologous genes from Mycobacterium smegmatis mc(2)155 were inactivated and mutants analyzed. Rv2358 protein was purified and found to bind upstream of the Rv2358 gene. Binding was inhibited by Zn(2+) ions.

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页码：5837 / 5840

页数：4

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