Two-way traffic: centrosomes and the cell cycle

被引:41
作者
Sluder, G [1 ]
机构
[1] Univ Massachusetts, Sch Med, Dept Cell Biol, Worcester, MA 01065 USA
关键词
D O I
10.1038/nrm1712
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The well recognized activities of the mammalian centrosome - microtubule nucleation, duplication, and organization of the primary cilium - are under the control of the cell cycle. However, the centrosome is more than just a follower of the cell cycle; it can also be essential for the cell to transit G1 and enter S phase. How the centrosome influences G1 progression is a mystery.
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收藏
页码:743 / 748
页数:6
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