Entorhinal cortex projection cells to the hippocampal formation in vitro

被引:23
作者
Dugladze, T [1 ]
Heinemann, U [1 ]
Gloveli, T [1 ]
机构
[1] Humboldt Univ, Charite, Johannes Muller Inst Physiol, D-10117 Berlin, Germany
关键词
projection neurons; entorhinal cortex; rhodamine-dextran-amine; patch-clamp; in vitro; rats;
D O I
10.1016/S0006-8993(01)02419-2
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Retrogradely labeled cells in superficial and deep layers of the entorhinal cortex (EC) were analyzed following application of the fluorescent tracer rhodamine-dextran-amine in different sites of the hippocampal Formation in a slice preparation. The results demonstrate a strong projection from layer IV/V to the dentate gyrus, that is in slices significantly stronger than that from layer II. In deep layers a large number of multipolar cells were found which were only labeled by dye application to the subiculum. Patch-clamp recordings from these cells revealed intrinsic low threshold membrane potential oscillations: suggesting their possible contribution to oscillatory network activity of the EC and subiculum. (C) 2001 Published by Elsevier Science B.V.
引用
收藏
页码:224 / 231
页数:8
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