A guide to 17β-hydroxysteroid dehydrogenases

被引:126
作者
Adamski, J
Jakob, FJ
机构
[1] GSF, Natl Res Ctr Hlth & Environm, Inst Expt Genet,Genome Anal Ctr, Mol Endocrinol & Proteom Grp, D-85764 Neuherberg, Germany
[2] Univ Wurzburg, Med Polyklin, Clin Res Unit, D-97070 Wurzburg, Germany
关键词
17 beta-hydroxysteroid dehydrogenase; steroid metabolism; nomenclature;
D O I
10.1016/S0303-7207(00)00383-X
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
17 beta -Hydroxysteroid dehydrogenases (17 beta -HSD) are pivotal in controlling the biological potency of steroid hormones by catalyzing oxidation or reduction at position 17. Several 17 beta -HSDs may as well metabolize further substrates including alcohols, bile acids. fatty acids and retinols. This review summarizes recent progress in the field of 17 beta -HSD research provides an update of nomenclature. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:1 / 4
页数:4
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