Perspectives on molecular computing

被引:14
作者
Hagiya, M [1 ]
机构
[1] Univ Tokyo, Grad Sch Sci, Dept Informat Sci, Bunkyo Ku, Tokyo 1130033, Japan
基金
日本学术振兴会;
关键词
molecular computing; DNA computing; bio-computing; artificial life;
D O I
10.1007/BF03037433
中图分类号
TP3 [计算技术、计算机技术];
学科分类号
0812 ;
摘要
In 1996, we began a research project on molecular computers under the new program "Research for the Future" funded by the Japan Society for the Promotion of Science. In this paper, we first summarize the research that has been completed in the field of DNA computing and the research problems that must be overcome. We also report some achievements of our research project in the first two years. We then propose a new direction in research towards autonomous molecular computers, and describe the author's work on the implementation of state machines using DNA molecules. We finally discuss the future perspectives on molecular computing based on our experiences.
引用
收藏
页码:131 / 151
页数:21
相关论文
共 32 条
[1]   MOLECULAR COMPUTATION OF SOLUTIONS TO COMBINATORIAL PROBLEMS [J].
ADLEMAN, LM .
SCIENCE, 1994, 266 (5187) :1021-1024
[2]   Organization of 'nanocrystal molecules' using DNA [J].
Alivisatos, AP ;
Johnsson, KP ;
Peng, XG ;
Wilson, TE ;
Loweth, CJ ;
Bruchez, MP ;
Schultz, PG .
NATURE, 1996, 382 (6592) :609-611
[3]  
ARITA M, 1997, IEEE INT C EV COMP, P243
[4]   A DNA based implementation of an evolutionary search for good encodings for DNA computation [J].
Deaton, R ;
Murphy, RC ;
Rose, JA ;
Garzon, M ;
Franceschetti, DR ;
Stevens, SE .
PROCEEDINGS OF 1997 IEEE INTERNATIONAL CONFERENCE ON EVOLUTIONARY COMPUTATION (ICEC '97), 1997, :267-271
[5]  
DEATON R, 1996, 2 ANN M DNA BAS COMP, P131
[6]   Cooperative amplification of templates by cross-hybridization (CATCH) [J].
Ehricht, R ;
Ellinger, T ;
McCaskill, JS .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1997, 243 (1-2) :358-364
[7]  
GARZON M, IN PRESS LNCS
[8]  
Gregoriadis G., 1984, LIPOSOME TECHNOLOGY, VI-III
[9]   ISOTHERMAL, INVITRO AMPLIFICATION OF NUCLEIC-ACIDS BY A MULTIENZYME REACTION MODELED AFTER RETROVIRAL REPLICATION [J].
GUATELLI, JC ;
WHITFIELD, KM ;
KWOH, DY ;
BARRINGER, KJ ;
RICHMAN, DD ;
GINGERAS, TR .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (05) :1874-1878
[10]  
Hagiya M, 1997, P 2 ANN GEN PROGR C, P105