Bioengineering the hair follicle: fringe benefits of stem cell technology

被引：81

作者：

Stenn, KS

Cotsarelis, G

机构：

[1] Univ Penn, Dept Dermatol, Sch Med, Philadelphia, PA 19104 USA

[2] Aderans Res Inst, Philadelphia, PA 19104 USA

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 2005年 / 16卷 / 05期

关键词：

D O I：

10.1016/j.copbio.2005.08.002

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent advances in epithelial stem cell biology have resulted in the isolation of hair follicle stem cells, which generate hair follicles when injected into immunodeficient mice. These isolated hair follicle epithelial stem cells must be combined with 'inductive' dermal cells to produce new hair follicles. The advent of techniques for cultivating inductive dermal cells and competent epithelial stem cells creates the opportunity to bioengineer hair follicles for the treatment of hair loss.

引用

收藏

页码：493 / 497

页数：5

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