Antiplatelet arylnaphthalide lignans from Justicia procumbens

被引：99

作者：

Chen, CC ^{[1
]}

Hsin, WC ^{[1
]}

Ko, FN ^{[1
]}

Huang, YL ^{[1
]}

Ou, JC ^{[1
]}

Teng, CM ^{[1
]}

机构：

[1] NATL TAIWAN UNIV,DEPT PHARMACOL,TAIPEI 10764,TAIWAN

来源：

JOURNAL OF NATURAL PRODUCTS | 1996年 / 59卷 / 12期

关键词：

D O I：

10.1021/np960443+

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Fractionation of the EtOH extract of Justicia procumbens, guided by antiplatelet bioassay, led to the isolation of nine known arylnaphthalide lignans, neojusticin A (1), justicidin B (2), justicidin A (3), taiwanin E methyl ether (4), neojusticin B (5), chinensinaphthol methyl ether (6), taiwanin E (8), chinensinaphthol (9), and diphyllin (10), and a new arylnaphthalide lignan that was characterized by spectral means as 4'-demethylchinensinaphthol methyl ether (7). Compounds 1, 2, 4, and 8 significantly inhibited platelet aggregation.

引用

页码：1149 / 1150

页数：2

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