Long-term humoral immunity against viruses: Revisiting the issue of plasma cell longevity

被引：80

作者：

Slifka, MK ^{[1
]}

Ahmed, R ^{[1
]}

机构：

[1] EMORY UNIV, SCH MED, DEPT MICROBIOL & IMMUNOL, ATLANTA, GA 30307 USA

来源：

TRENDS IN MICROBIOLOGY | 1996年 / 4卷 / 10期

关键词：

D O I：

10.1016/0966-842X(96)10059-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Despite extensive documentation of prolonged antibody responses following vaccination or acute viral infection, the mechanisms behind long-term antibody production are nor fully understood. We propose the hypothesis that long-lived plasma cells are an important, yet largely overlooked, component of long-term humoral immunity.

引用

页码：394 / 400

页数：7

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