Triterpene Saponins from Clematis chinensis and Their Potential Anti-inflammatory Activity

被引：70

作者：

Fu, Qiang ^{[1
]}

Zan, Ke ^{[1
]}

Zhao, Mingbo ^{[1
]}

Zhou, Sixiang ^{[1
]}

Shi, Shepo ^{[1
]}

Jiang, Yong ^{[1
]}

Tu, Pengfei ^{[1
]}

机构：

[1] Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China

来源：

JOURNAL OF NATURAL PRODUCTS | 2010年 / 73卷 / 07期

关键词：

CONSTITUENTS; OSBECK; ROOT; RHIZOMES;

D O I：

10.1021/np100057y

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Seven new triterpene saponins, clematochinenosides A-G (1-7), together with 17 known saponins (8-24), were isolated from the roots and rhizomes of Clematis chinensis. Their structures were elucidated on the basis of spectroscopic evidence and hydrolysis products. Compounds 1, 3-7, and 20-24 showed inhibitory activities against COX-1 and COX-2 enzymes.

引用

页码：1234 / 1239

页数：6

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