Recent advances in sugar-based excipients

被引:13
作者
Bowe, KE [1 ]
机构
[1] SPL Polyols, New Castle, DE 19720 USA
来源
PHARMACEUTICAL SCIENCE & TECHNOLOGY TODAY | 1998年 / 1卷 / 04期
关键词
D O I
10.1016/S1461-5347(98)00043-1
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Sugar-based excipients have enjoyed broad acceptance as ingredients in pharmaceutical tableting. They can be used to mask, or render more palatable, the bitter taste of active agents, As direct compression has become the preferred method of tablet manufacture, demand has increased for compressible sugar-based excipients. The author illustrates some recent advances with recent case studies of tests on two new excipients, crystalline maltose and directly compressible sucrose (containing sorbitol).
引用
收藏
页码:166 / 173
页数:8
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