In vitro activity of linezolid against multiply resistant Gram-positive clinical isolates

被引：54

作者：

Cercenado, E ^{[1
]}

García-Garrote, F ^{[1
]}

Bouza, E ^{[1
]}

机构：

[1] Hosp Gen Univ Gregorio Maranon, Microbiol Serv, Madrid 28007, Spain

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 2001年 / 47卷 / 01期

关键词：

D O I：

10.1093/jac/47.1.77

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The in vitro activity of the oxazolidinone linezolid was compared with the activities of vancomycin and telcoplanin against 450 Gram-positive clinical isolates, including a variety of multiply resistant strains. Linezolid inhibited all microorganisms tested at less than or equal to4 mg/L, including methicillin- and teicoplanin-resistant staphylococci, glycopeptide-resistant enterococci, penicillin- and multiply resistant pneumococci and viridans streptococci, and erythromycin-resistant beta -haemolytic streptococci. The MIC90 of linezolid for all isolates was 2 mg/L.

引用

页码：77 / 81

页数：5

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