Solid phase synthesis of oligosaccharides

被引：36

作者：

Adinolfi, M ^{[1
]}

Barone, G ^{[1
]}

DeNapoli, L ^{[1
]}

Iadonisi, A ^{[1
]}

Piccialli, G ^{[1
]}

机构：

[1] UNIV NAPLES FEDERICO II,DIPARTIMENTO CHIM ORGAN & BIOL,I-80134 NAPLES,ITALY

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 28期

关键词：

D O I：

10.1016/0040-4039(96)01020-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient and stereocontrolled solid-phase chemical synthesis of oligosaccarides using a new type of insoluble support (a copolymer of polyethylene glycol and polystyrene) is described. Several Lewis acids were tested as activators of the trichloroacetimidate 12, used as glycosyl donor, in the dimer 13 formation. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：5007 / 5010

页数：4

共 20 条

[1] TOWARDS THE CHEMICAL SYNTHESIS OF PROTEINS
BAYER, E
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1991, 30 (02): : 113 - 129
[2] SYNTHESIS OF GLYCOSIDES OF FUCOSE UNDER NEUTRAL CONDITIONS IN SOLUTIONS OF LICLO4 IN ORGANIC-SOLVENTS
BOHM, G
WALDMANN, H
[J]. TETRAHEDRON LETTERS, 1995, 36 (22) : 3843 - 3846
[3] BOONS GI, 1996, TETRAHEDRON, V4, P1095
[4] A STRATEGY FOR THE SOLID-PHASE SYNTHESIS OF OLIGOSACCHARIDES
DANISHEFSKY, SJ
MCCLURE, KF
RANDOLPH, JT
RUGGERI, RB
[J]. SCIENCE, 1993, 260 (5112) : 1307 - 1309
[5] AUTOMATED SOLID-PHASE SYNTHESIS OF CYCLIC OLIGONUCLEOTIDES - A FURTHER IMPROVEMENT
DENAPOLI, L
GALEONE, A
MAYOL, L
MESSERE, A
MONTESARCHIO, D
PICCIALLI, G
[J]. BIOORGANIC & MEDICINAL CHEMISTRY, 1995, 3 (10) : 1325 - 1329
[6] POLYMER-SUPPORTED SOLUTION SYNTHESIS OF OLIGOSACCHARIDES
DOUGLAS, SP
WHITFIELD, DM
KREPINSKY, JJ
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (13) : 5095 - 5097
[7] NUCLEAR MAGNETIC-RESONANCE STUDIES OF 1,6-LINKED DISACCHARIDES
FORSGREN, M
JANSSON, PE
KENNE, L
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1985, (11): : 2383 - 2388
[8] H-PHOSPHONATE OLIGONUCLEOTIDE SYNTHESIS ON A POLYETHYLENE-GLYCOL POLYSTYRENE COPOLYMER
GAO, HT
GAFFNEY, BL
JONES, RA
[J]. TETRAHEDRON LETTERS, 1991, 32 (40) : 5477 - 5480
[9] BENZYL TRICHLOROACETIMIDATE, A VERSATILE REAGENT FOR ACID-CATALYZED BENZYLATION OF HYDROXY-GROUPS
IVERSEN, T
BUNDLE, DR
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1981, (23) : 1240 - 1241
[10] SELECTINS - INTERPRETERS OF CELL-SPECIFIC CARBOHYDRATE INFORMATION DURING INFLAMMATION
LASKY, LA
[J]. SCIENCE, 1992, 258 (5084) : 964 - 969

← 1 2 →