Estrogen receptor dinucleotide repeat polymorphism is associated with minimal or mild endometriosis

被引：36

作者：

Kim, SH

Choi, YM

Jun, JK

Kim, SH

Kim, JG

Moon, SY

机构：

[1] Seoul Natl Univ, Coll Med, Med Res Ctr, Inst Reprod Med & Populat,Dept Obstet & Gynecol, Seoul 110744, South Korea

[2] Univ Ulsan, Asan Med Ctr, Coll Med, Dept Obstet & Gynecol, Seoul, South Korea

来源：

FERTILITY AND STERILITY | 2005年 / 84卷 / 03期

关键词：

D O I：

10.1016/j.fertnstert.2005.03.046

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The present study was designed to explore the association between estrogen receptor-a gene polymorphism and the risk of endometriosis by investigating the frequecy of PvuII, XbaI, and thymine-adenine (TA) repeat polymorphisms in patients with and without endometriosis in a Korean population. Although there was no significant difference in the allele distribution and frequency of either PvuII or Xbal polymorphisms between endometriosis patients and control subjects, patients with stage I/II endometriosis showed a higher incidence of alleles with fewer (TA)n repeats (12-15 repeats) compared with controls.

引用

页码：774 / 777

页数：4

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