S-Adenosylmethionine and protein methylation

被引:46
作者
Grillo, MA [1 ]
Colombatto, S [1 ]
机构
[1] Univ Turin, Sez Biochim, Dipartimento Med & Oncol Sperimentale, Turin, Italy
关键词
protein methyltransferases; isoaspartyl residues; protein phosphatase; 2A; histones; isoprenylcysteine;
D O I
10.1007/s00726-005-0197-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The enzymes responsible for protein methylation by S-adenosylmethionine, both at the carboxyl groups and at the nitrogen groups, are reviewed. The possibility that the reactions involved may be reversible is also considered.
引用
收藏
页码:357 / 362
页数:6
相关论文
共 51 条
[1]   Structural basis for Ca2+-induced activation of human PAD4 [J].
Arita, K ;
Hashimoto, H ;
Shimizu, T ;
Nakashima, K ;
Yamada, M ;
Sato, M .
NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2004, 11 (08) :777-783
[2]   The influence of protein structure on the products emerging from succinimide hydrolysis [J].
Athiner, L ;
Kindrachuk, J ;
Georges, F ;
Napper, S .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (34) :30502-30507
[3]   ISOPRENYLATION IS REQUIRED FOR THE PROCESSING OF THE LAMIN-A PRECURSOR [J].
BECK, LA ;
HOSICK, TJ ;
SINENSKY, M .
JOURNAL OF CELL BIOLOGY, 1990, 110 (05) :1489-1499
[4]   Arginine methylation inhibits the binding of proline-rich ligands to Src homology 3, but not WW, domains [J].
Bedford, MT ;
Frankel, A ;
Yaffe, MB ;
Clarke, S ;
Leder, P ;
Richard, S .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (21) :16030-16036
[5]   Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf [J].
Bergo, MO ;
Gavino, BJ ;
Hong, C ;
Beigneux, AP ;
McMahon, M ;
Casey, PJ ;
Young, SG .
JOURNAL OF CLINICAL INVESTIGATION, 2004, 113 (04) :539-550
[6]   Asymmetric dimethylarginine, and endogenous inhibitor of nitric oxide synthase, explains the "L-arginine paradox" and acts as a novel cardiovascular risk factor [J].
Böger, RH .
JOURNAL OF NUTRITION, 2004, 134 (10) :2842S-2847S
[7]   Characterization of dimethylargininase from bovine brain:: Evidence for a zinc binding site [J].
Bogumil, R ;
Knipp, M ;
Fundel, SM ;
Vasák, M .
BIOCHEMISTRY, 1998, 37 (14) :4791-4798
[8]   Regulation of transcription by a protein methyltransferase [J].
Chen, DG ;
Ma, H ;
Hong, H ;
Koh, SS ;
Huang, SM ;
Schurter, BT ;
Aswad, DW ;
Stallcup, MR .
SCIENCE, 1999, 284 (5423) :2174-2177
[9]   Regulation of p53 activity through lysine methylation [J].
Chuikov, S ;
Kurash, JK ;
Wilson, JR ;
Xiao, B ;
Justin, N ;
Ivanov, GS ;
McKinney, K ;
Tempst, P ;
Prives, C ;
Gamblin, SJ ;
Barlev, NA ;
Reinberg, D .
NATURE, 2004, 432 (7015) :353-360