The activity of meropenem and comparators against Acinetobacter strains isolated from European hospitals, 1997-2000

被引：55

作者：

Turner, PJ ^{[1
]}

Greenhalgh, JM ^{[1
]}

机构：

[1] AstraZeneca, Antibiot Dev & Tech Support Grp, Macclesfield SK10 4TF, Cheshire, England

来源：

CLINICAL MICROBIOLOGY AND INFECTION | 2003年 / 9卷 / 06期

关键词：

antibiotics; carbapenems; Acinetobacter; MYSTIC; meropenem;

D O I：

10.1046/j.1469-0691.2003.00591.x

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

In vitro susceptibilities to meropenem and comparators of Acinetobacter strains isolated from serious infections in 37 European hospital centers participating in the Meropenem Yearly Susceptibility Test Information Collection (MYSTIC) Program (1997-2000) were tested. There were 635 Acinetobacter strains collected: 490 A. baumannii ; 51 A. calcoaceticus var. lwoffii ; and 94 other Acinetobacter strains. Overall, meropenem and imipenem were the most effective agents tested. Resistance to the antimicrobials was: 14%, meropenem; 16%, imipenem; 39%, piperacillin-tazobactam; 41%, tobramycin; 45%, ceftazidime; and 53%, ciprofloxacin. Thus, the carbapenems have useful activity against Acinetobacter spp. and represent a viable choice for treating infections caused by these organisms.

引用

页码：563 / 567

页数：5

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