Moderate alcohol consumption: effects on lipids and cardiovascular disease risk

被引:57
作者
van Tol, A
Hendriks, HFJ
机构
[1] Erasmus Univ, Inst Cardiovasc Res, Dept Biochem, NL-3000 DR Rotterdam, Netherlands
[2] TNO Nutr & Food Res, Dept Nutr Physiol, Zeist, Netherlands
关键词
D O I
10.1097/00041433-200102000-00004
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Light to moderate alcohol consumption is associated with a reduced risk of coronary heart disease, as well as ischaemic stroke and possibly type 2 diabetes. Epidemiological and physiological data are in favour of a causal relationship. Proposed protective mechanisms include the stimulation of HDL-mediated processes such as reverse cholesterol transport and antioxidative effects. More well-controlled studies are needed to provide a complete understanding of the complexity of the underlying physiological mechanisms. Curr Opin Lipidol 12:19-23, (C) 2001 Lippincott Williams & Wilkins.
引用
收藏
页码:19 / 23
页数:5
相关论文
共 71 条
[1]   Alcohol consumption and risk of type 2 diabetes mellitus among US male physicians [J].
Ajani, UA ;
Hennekens, CH ;
Spelsberg, A ;
Manson, JE .
ARCHIVES OF INTERNAL MEDICINE, 2000, 160 (07) :1025-1030
[2]   Moderate alcohol consumption and the risk of sudden cardiac death among US male physicians [J].
Albert, CM ;
Manson, JE ;
Cook, NR ;
Ajani, UA ;
Gaziano, JM ;
Hennekens, CH .
CIRCULATION, 1999, 100 (09) :944-950
[3]   COGNITIVE-FUNCTIONING IN YOUNG SOCIAL DRINKERS - IS THERE IMPAIRMENT TO DETECT [J].
BATES, ME ;
TRACY, JI .
JOURNAL OF ABNORMAL PSYCHOLOGY, 1990, 99 (03) :242-249
[4]  
Bell JRC, 2000, AM J CLIN NUTR, V71, P103
[5]   Light-to-moderate alcohol consumption and the risk of stroke among US male physicians. [J].
Berger, K ;
Ajani, UA ;
Kase, CS ;
Gaziano, JM ;
Buring, JE ;
Glynn, RJ ;
Hennekens, CH .
NEW ENGLAND JOURNAL OF MEDICINE, 1999, 341 (21) :1557-1564
[6]  
Breteler MMB, 1998, HAEMOSTASIS, V28, P167
[7]  
BRETELER MMB, 1997, J NEUROL, V37, P1295
[8]  
Caccetta RAA, 2000, AM J CLIN NUTR, V71, P67
[9]   Moderate alcohol consumption and risk for angina pectoris or myocardial infarction in US male physicians [J].
Camargo, CA ;
Stampfer, MJ ;
Glynn, RJ ;
Grodstein, F ;
Gaziano, JM ;
Manson, JE ;
Buring, JE ;
Hennekens, CH .
ANNALS OF INTERNAL MEDICINE, 1997, 126 (05) :372-375
[10]  
Cao GH, 1998, CLIN CHEM, V44, P1309