New reactions of IBX: Oxidation of nitrogen- and sulfur-containing substrates to afford useful synthetic intermediates

被引：237

作者：

Nicolaou, KC

Mathison, CJN

Montagnon, T

机构：

[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA

[2] Scripps Res Inst, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA

[3] Univ Calif San Diego, Dept Biochem & Chem, La Jolla, CA 92093 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2003年 / 42卷 / 34期

关键词：

imines; nitrogen heterocycles; oxidation; oximes; synthetic methods;

D O I：

10.1002/anie.200352076

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

New reactions for the synthetic toolbox: 2-lodoxybenzoic acid (IBX) was employed to access a diverse array of useful synthetic intermediates. Among other transformations, the developed chemistry converts amines into imines, dithianes into carbonyl groups, N-heterocycles into N-heteroaromatic compounds, and hydroxylamines into oximes in high yields.

引用

页码：4077 / 4082

页数：6

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