GCN2 whets the appetite for amino acids

被引：51

作者：

Dever, TE ^{[1
]}

Hinnebusch, AG ^{[1
]}

机构：

[1] NICHHD, Lab Gene Regulat & Dev, NIH, Bethesda, MD 20892 USA

来源：

MOLECULAR CELL | 2005年 / 18卷 / 02期

关键词：

D O I：

10.1016/j.molcel.2005.03.023

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In response to amino acid starvation, the kinase GCN2 in yeast activates amino acid biosynthesis. Two recent studies (Maurin et al., 2005; Hao et al., 2005) reveal that GCN2 in the brain of mice restricts intake of diets lacking essential amino acids.

引用

页码：141 / 142

页数：2

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