An improved method for the palladium-catalyzed amination of aryl iodides

被引:140
作者
Ali, MH [1 ]
Buchwald, SL [1 ]
机构
[1] MIT, Dept Chem, Cambridge, MA 02139 USA
关键词
D O I
10.1021/jo0008486
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Aryl iodides are coupled with amines to give the corresponding arylamines in high yield in the presence of palladium, a suitable ligand, and NaOt-Bu. Functionalized aryl iodides give good yields of the corresponding arylamines when Cs2CO3 is substituted as the base.
引用
收藏
页码:2560 / 2565
页数:6
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