A convenient synthetic route to polypyridine-esters by palladium-promoted carboalkoxylation

被引：24

作者：

El-ghayoury, A ^{[1
]}

Ziessel, R ^{[1
]}

机构：

[1] Ecole Chim Polymeres Mat ECPM, Lab Chim Elect & Photon Mol, CNRS, F-67008 Strasbourg, France

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 25期

关键词：

D O I：

10.1016/S0040-4039(98)00820-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Pyridine and oligopyridines bearing halide or triflate groups react smoothly with CO (1 atm) and n-butanol in the presence of a tertiary amine and a catalytic amount of bis(triphenylphosphine)palladium dichloride to afford the corresponding esters. When ethanol and a disubstituted substrate are used under milder conditions, selective mono-carboalkoxylation occurs. Amidation is effected using a primary amine as nucleophile. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：4473 / 4476

页数：4

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