Molecular biology - Damage control

被引：5

作者：

Azzalin, Claus M. ^{[1
]}

Lingner, Joachim ^{[1
]}

机构：

[1] Ecole Polytech Fed Lausanne, Inst Suisse Rech Expt Canc, Frontiers Genet Natl Ctr Competence Res, CH-1066 Epalinges, Switzerland

来源：

NATURE | 2007年 / 448卷 / 7157期

关键词：

D O I：

10.1038/4481001a

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 [理学]; 0710 [生物学]; 09 [农学];

摘要：

The chemical composition of normal DNA at the end of chromosomes does not differ from that of damaged and broken DNA within chromosomes. New findings hint at how the DNA-repair machinery distinguishes the two.

引用

页码：1001 / 1002

页数：2

共 13 条

[1]

ARNERIC M, IN PRESS EMBO REP

[2]

Increased association of telomerase with short telomeres in yeast [J].

Bianchi, Alessandro ;

Shore, David .

GENES & DEVELOPMENT, 2007, 21 (14) :1726-1730

[3]

Extension of life-span by introduction of telomerase into normal human cells [J].

Bodnar, AG ;

Ouellette, M ;

Frolkis, M ;

Holt, SE ;

Chiu, CP ;

Morin, GB ;

Harley, CB ;

Shay, JW ;

Lichtsteiner, S ;

Wright, WE .

SCIENCE, 1998, 279 (5349) :349-352

[4]

CHANG M, IN PRESS GENES DEV

[5]

d'Adda diFagagna F., 2003, Nature, V426, P194, DOI DOI 10.1038/NATURE02118

[6]

Shelterin: the protein complex that shapes and safeguards human telomeres [J].

de Lange, T .

GENES & DEVELOPMENT, 2005, 19 (18) :2100-2110

[7]

Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1 [J].

Denchi, Eros Lazzerini ;

de lange, Titia .

NATURE, 2007, 448 (7157) :1068-1071

[8]

Circular chromosome formation in a fission yeast mutant defective in two ATM homologues [J].

Naito, T ;

Matsuura, A ;

Ishikawa, F .

NATURE GENETICS, 1998, 20 (02) :203-206

[9]

Ritchie KB, 1999, MOL CELL BIOL, V19, P6065

[10]

Telomerase and Tel1p preferentially associate with short telomeres in S-cerevisiae [J].

Sabourin, Michelle ;

Tuzon, Creighton T. ;

Zakian, Virginia A. .

MOLECULAR CELL, 2007, 27 (04) :550-561

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