Isothiazoles. Part 12: Isothiazolylphosphonates, a new class of isothiazole dioxides

被引：18

作者：

Clerici, F

Gelmi, ML

Pini, E

Valle, M

机构：

[1] Univ Milan, Fac Farm, I-20133 Milan, Italy

[2] Univ Milan, Ist Chim Organ, Ctr Interuniv Ric Reaz Pericicliche & Sintesi Sis, I-20133 Milan, Italy

来源：

TETRAHEDRON | 2001年 / 57卷 / 25期

关键词：

isothiazoles; phosphonates; sulfur heterocycles; cycloaddition reactions;

D O I：

10.1016/S0040-4020(01)00448-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We describe a mild and efficient method to prepare 3-amino-4,5-dihydro-5-isothiazolylphosphonates from 3-amino-5-unsubstituted isothiazole dioxides. Starting from 3-amino-5-bromo-isothiazole dioxides either 3-amino-5-isothiazolylphosphonates or 5-diethoxyphosphoryl-4,5-dihydro-4-isothiazolylphosphonates were prepared. Isothiazolylphosphonates represent a new class of isothiazole dioxides. Some preliminary investigations on the reactivity with 1,3-dipoles were reported. (C) 2001 Elsevier Science Ltd. All rights reserved.

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收藏

页码：5455 / 5459

页数：5

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