Creatinine clearance and hemoglobin concentration before and after heart transplantation

被引：6

作者：

Cirillo, M ^{[1
]}

De Santo, LS ^{[1
]}

Pollastro, RM ^{[1
]}

Romano, G ^{[1
]}

Mastroiacono, C ^{[1
]}

Maiello, C ^{[1
]}

Amarelli, C ^{[1
]}

Di Stazio, E ^{[1
]}

Perna, A ^{[1
]}

Anastasio, P ^{[1
]}

机构：

[1] Univ Naples 2, Dept Nephrol & Heart Surg, Naples, Italy

来源：

SEMINARS IN NEPHROLOGY | 2005年 / 25卷 / 06期

关键词：

creatinine; glomerular filtration rate; congestive heart failure; heart transplantation; mortality;

D O I：

10.1016/j.semnephrol.2005.05.012

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Clinical studies indicate that indices of glomerular filtration rate (GFR) as serum creatinine or creatinine clearance can predict the risk of death in congestive heart failure (CHF) and in heart transplantation. The study reports data on creatinine clearance before and after heart transplantation in 160 patients followed-up for 5 years at our Unit. Pre-transplant creatinine clearance averaged 83.5 +/- 32 mL/min x 1.73 m(2) and was not significantly associated with 5-year mortality. Creatinine clearance significantly decreased after heart transplantation with a linear trend up to 3 years for patients with complete follow-up. Data suggest that the relation between kidney function and mortality after heart transplantation is affected by several confounders with inclusion of cause of heart disease, co-morbidity, anemia, and post-transplant decrease in kidney function.

引用

页码：413 / 418

页数：6

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