Novel lysophospholipase A secreted by Legionella pneumophila

被引：49

作者：

Flieger, A

Gong, SM

Faigle, M

Stevanovic, S

Cianciotto, NP

Neumeister, B

机构：

[1] Northwestern Univ, Sch Med, Dept Immunol Microbiol, Chicago, IL 60611 USA

[2] Univ Klinikum Tubingen, Abt Transfus Med, D-72076 Tubingen, Germany

[3] Univ Tubingen, Immunol Abt, Interfak Inst Zellbiol, D-72076 Tubingen, Germany

来源：

JOURNAL OF BACTERIOLOGY | 2001年 / 183卷 / 06期

关键词：

D O I：

10.1128/JB.183.6.2121-2124.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We show that Legionella pneumophila possesses lysophospholipase A activity, which releases fatty acids from lysophosphatidylcholine. The NH2-terminal sequence of the enzyme contained FGDSLS, corresponding to a catalytic domain in a recently described group of lipolytic enzymes, Culture supernatants of a L. pneumophila pilD mutant lost the ability to cleave lysophosphatidylcholine.

引用

收藏

页码：2121 / 2124

页数：4

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