UV inactivation of Cryptosporidium hominis as measured in cell culture

被引:30
作者
Johnson, AM
Linden, K
Ciociola, KM
De Leon, R
Widmer, G
Rochelle, PA
机构
[1] Metropolitan Water Dist So Calif, Water Qual Lab, La Verne, CA 91750 USA
[2] Duke Univ, Dept Civil & Environm Engn, Durham, NC 27706 USA
[3] Tufts Univ, Sch Vet Med, Div Infect Dis, North Grafton, MA 01536 USA
关键词
D O I
10.1128/AEM.71.5.2800-2802.2005
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The Cryptosporidium spp. UV disinfection studies conducted to date have used Cryptosporidium parvum oocysts. However, Cryptosporidium hominis predominates in human cryptosporidiosis infections, so there is a critical need to assess the efficacy of UV disinfection of C hominis. This study utilized cell culture-based methods to demonstrate that C. hominis oocysts displayed similar levels of infectivity and had the same sensitivity to UV light as C. parvum. Therefore, the water industry can be confident about extrapolating C. parvum UV disinfection data to C. hominis oocysts.
引用
收藏
页码:2800 / 2802
页数:3
相关论文
共 24 条
[1]   Genetic analysis of a Cryptosporidium parvum human genotype 1 isolate passaged through different host species [J].
Akiyoshi, DE ;
Feng, X ;
Buckholt, MA ;
Widmer, G ;
Tzipori, S .
INFECTION AND IMMUNITY, 2002, 70 (10) :5670-5675
[2]  
[Anonymous], FED REG
[3]  
[Anonymous], CRYPTOSPORIDIUM CRYP
[4]  
Clancy JL, 2004, J AM WATER WORKS ASS, V96, P84, DOI 10.1002/j.1551-8833.2004.tb10576.x
[5]   Inactivation of Cryptosporidium parvum oocysts using medium- and low-pressure ultraviolet radiation [J].
Craik, SA ;
Weldon, D ;
Finch, GR ;
Bolton, JR ;
Belosevic, M .
WATER RESEARCH, 2001, 35 (06) :1387-1398
[6]   Epidemiology of Cryptosporidium:: transmission, detection and identification [J].
Fayer, R ;
Morgan, U ;
Upton, SJ .
INTERNATIONAL JOURNAL FOR PARASITOLOGY, 2000, 30 (12-13) :1305-1322
[7]   Molecular analysis of the 18S rRNA gene of Cryptosporzdium parasites from patients with or without human immunodeficiency virus infections living in Kenya, Malawi, Brazil, the United Kingdom, and Vietnam [J].
Gatei, W ;
Greensill, J ;
Ashford, RW ;
Cuevas, LE ;
Parry, CM ;
Cunliffe, NA ;
Beeching, NJ ;
Hart, CA .
JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (04) :1458-1462
[8]   Sporadic cryptosporidiosis case-control study with genotyping [J].
Hunter, PR ;
Hughes, S ;
Woodhouse, S ;
Syed, Q ;
Verlander, NQ ;
Chalmers, RM ;
Morgan, K ;
Nichols, G ;
Beeching, N ;
Osborn, K .
EMERGING INFECTIOUS DISEASES, 2004, 10 (07) :1241-1249
[9]   Community surveys of self-reported diarrhoea can dramatically overestimate the size of outbreaks of waterborne cryptosporidiosis [J].
Hunter, PR ;
Syed, Q .
WATER SCIENCE AND TECHNOLOGY, 2001, 43 (12) :27-30
[10]   Inter-laboratory comparison of the CD-1 neonatal mouse logistic dose-response model for Cryptosporidium parvum oocysts [J].
Korich, DG ;
Marshall, MM ;
Smith, HV ;
O'Grady, J ;
Bukhari, Z ;
Fricker, CR ;
Rosen, JP ;
Clancy, JL .
JOURNAL OF EUKARYOTIC MICROBIOLOGY, 2000, 47 (03) :294-298