Palladium-catalyzed amination in the synthesis of macrocycles comprising cholane, polyamine and pyridine units

被引：22

作者：

Averin, Alexei D. ^{[1
]}

Ranyuk, Elena R. ^{[1
]}

Lukashev, Nikolai V. ^{[1
]}

Golub, Svetlana L. ^{[2
]}

Buryak, Alexel K. ^{[2
]}

Beletskaya, Irina P. ^{[1
,2
]}

机构：

[1] Moscow MV Lomonosov State Univ, Dept Chem, Moscow 119992, Russia

[2] AN Frumkin Electrochem Inst, Moscow 119991, Russia

来源：

TETRAHEDRON LETTERS | 2008年 / 49卷 / 07期

基金：

俄罗斯基础研究基金会;

关键词：

D O I：

10.1016/j.tetlet.2007.12.049

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3,24-Bis(6-chloropyridin-2-yloxy)cholane, obtained from 3,24-cholandiol via a Mitsunobu reaction, was successfully used for the synthesis of a variety of polyazamacrocycles using Pd-catalyzed amination reaction with linear polyamines. The competing formation of cyclodimers and other cyclic oligomers was found to be strongly dependent on the nature of the polyamines employed. (C) 2007 Elsevier Ltd. All rights reserved.

引用

页码：1188 / 1191

页数：4

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