Cellular transplants: steps toward restoration of function in spinal injured animals

被引：25

作者：

Murray, M ^{[1
]}

机构：

[1] Drexel Univ, Coll Med, Dept Neurobiol & Anat, Philadelphia, PA 19129 USA

来源：

BRAIN MECHANISMS FOR THE INTEGRATION OF POSTURE AND MOVEMENT | 2004年 / 143卷

关键词：

D O I：

10.1016/S0079-6123(03)43013-6

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Severe spinal cord injury results in severe, persisting deficits with little hope for substantial recovery. Recent developments in transplantation protocols, gene therapy, and methods of evaluation now offer hope of developing treatments that will lead to better prognoses. This review discusses the consequences of spinal injury, animal models used to study injury and recovery, types of cellular transplants, selection of behavioral and physiological tests of recovery, and ways to test the efficacy of the interventions and to improve transplant-mediated recovery.

引用

页码：133 / 146

页数：14

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