Magnesium-Catalyzed Hydroboration of Pyridines

被引：207

作者：

Arrowsmith, Merle ^{[1
]}

Hill, Michael S. ^{[1
]}

Hadlington, Terrance ^{[1
]}

Kociok-Koehn, Gabriele ^{[1
]}

Weetman, Catherine ^{[1
]}

机构：

[1] Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England

来源：

ORGANOMETALLICS | 2011年 / 30卷 / 21期

基金：

英国工程与自然科学研究理事会;

关键词：

HETEROCYCLES; BUTYLLITHIUM; COMPLEXES; CALCIUM; ADDUCT;

D O I：

10.1021/om2008138

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Reaction of catalytic quantities of a beta-diketiminato n-butylmagnesium complex with pinacol-borane in the presence of pyridine derivatives provides facile access to borylated dihydropyridines. The reaction is applicable to a wide range of monocyclic and fused-ring pyridine derivatives and catalytic turnover is proposed to occur through a well-defined sequence of Mg-H/pyridine dearomatization and Mg-N/B-H sigma bond metathesis steps.

引用

收藏

页码：5556 / 5559

页数：4

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