Genes, variation of cholesterol and fat intake and serum lipids

被引:45
作者
Ordovas, JM [1 ]
Schaefer, EJ [1 ]
机构
[1] Tufts Univ, JM USDA Human Nutr Res Ctr Ageing, Lipid Metab Lab, Boston, MA 02111 USA
关键词
D O I
10.1097/00041433-199902000-00004
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Several studies have examined gene-diet interactions in the response of plasma lipid concentrations to changes in dietary fat and/or cholesterol. Among the gene loci examined, APOE has been the most studied, and the current evidence suggests that this locus might be responsible for some of the interindividual variability in dietary response. Other loci, including APOA4, APOA1 and APOB have also been found to account for some of the variability in the fasting and fed states. Curr Opin Lipidol 10:15-22. (C) 1999 Lippincott Williams & Wilkins.
引用
收藏
页码:15 / 22
页数:8
相关论文
共 33 条
[1]   Urbanization elicits a more atherogenic lipoprotein profile in carriers of the apolipoprotein A-IV-2 allele than in A-IV-1 homozygotes [J].
Campos, H ;
LopezMiranda, J ;
Rodriguez, C ;
Albajar, M ;
Schaefer, EJ ;
Ordovas, JM .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 1997, 17 (06) :1074-1081
[2]  
Connor WE, 1997, NEW ENGL J MED, V337, P562
[3]   Postprandial dyslipidemia: A risk factor for coronary heart disease [J].
Dallongeville, J ;
Fruchart, JC .
ANNALS OF NUTRITION AND METABOLISM, 1998, 42 (01) :1-11
[4]   Effects of family history of heart disease, apolipoprotein E phenotype, and lipoprotein(a) on the response of children's plasma lipids to change in dietary lipids [J].
Dixon, LB ;
Shannon, BM ;
Tershakovec, AM ;
Bennett, MJ ;
Coates, PM ;
Cortner, JA .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1997, 66 (05) :1207-1217
[5]   Cholesteryl ester transfer protein gene polymorphism is a determinant of HDL cholesterol and of the lipoprotein response to a lipid-lowering diet in type 1 diabetes [J].
Dullaart, RPF ;
Hoogenberg, K ;
Riemens, SC ;
Groener, JEM ;
vanTol, A ;
Sluiter, WJ ;
Stulp, BK .
DIABETES, 1997, 46 (12) :2082-2087
[6]  
Grundy Scott M., 1997, American Journal of Clinical Nutrition, V66, p988S, DOI 10.1093/ajcn/66.4.988S
[7]   Effect of 347-serine mutation in apoprotein A-IV on plasma LDL cholesterol response to dietary fat [J].
Jansen, S ;
LopezMiranda, J ;
Salas, J ;
Ordovas, JM ;
Castro, P ;
Marin, C ;
Ostos, MA ;
LopezSegura, F ;
JimenezPereperez, JA ;
Blanco, A ;
PerezJimenez, F .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 1997, 17 (08) :1532-1538
[8]  
Jansen S, 1997, J LIPID RES, V38, P1995
[9]  
Katan MB, 1997, NEW ENGL J MED, V337, P563
[10]   Nutrient-gene interactions determine mitochondrial function: effect of dietary fat [J].
Kim, MJC ;
Berdanier, CD .
FASEB JOURNAL, 1998, 12 (02) :243-248