Genomic structure and promoter characterization of the human ACTH receptor gene

被引：47

作者：

Naville, D ^{[1
]}

Jaillard, C ^{[1
]}

Barjhoux, L ^{[1
]}

Durand, P ^{[1
]}

Begeot, M ^{[1
]}

机构：

[1] HOP DEBROUSSE, INSERM, INRA, U418, F-69322 LYON 05, FRANCE

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1997年 / 230卷 / 01期

关键词：

D O I：

10.1006/bbrc.1996.5911

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

One kb of the 5'-flanking region of the human ACTH receptor gene was isolated and partially characterized. Transient transfections with hGH reporter confirmed the promoter activity in Y1 cells. Putative elements for transcription factors involved in regulation were noted in the sequence. The promoter activity of some of the constructs is responsive to a treatment by forskolin, due to the presence of several CRE-like sequences. (C) 1997 Academic Press

引用

页码：7 / 12

页数：6

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