SUMOylation-regulated Protein Phosphorylation, Evidence from Quantitative Phosphoproteomics Analyses

被引：53

作者：

Yao, Qi ^{[1
]}

Li, Hui ^{[1
]}

Liu, Bing-Qian ^{[1
]}

Huang, Xin-Yun ^{[3
]}

Guo, Lin ^{[1
,2
]}

机构：

[1] Wuhan Univ, Coll Life Sci, State Key Lab Virol, Wuhan 430072, Peoples R China

[2] Wuhan Univ, Minist Educ, Key Lab Analyt Chem Biol & Med, Wuhan 430072, Peoples R China

[3] Cornell Univ, Weill Med Coll, Dept Physiol, New York, NY 10065 USA

来源：

JOURNAL OF BIOLOGICAL CHEMISTRY | 2011年 / 286卷 / 31期

基金：

美国国家科学基金会;

关键词：

TYROSINE-PHOSPHATASE; 1B; SUMO; IDENTIFICATION; SITES;

D O I：

10.1074/jbc.M111.220848

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

Protein modification is critical for the regulation of protein functions. Cross-talks among different types of protein modifications should yield concerted and coordinated regulatory networks for physiological functions. Here we have employed system-wide and quantitative phosphoproteomics analyses to reveal a global cross-talk for SUMOylation-modulated phosphorylation. Furthermore, as specific examples, we have shown that the alpha subunit of casein kinase II is SUMOylated and that this affects the phosphorylation of its substrates. SUMO-regulated phosphorylation is involved in cell cycle control. Our data demonstrate an interplay between protein SUMOylation and phosphorylation and imply a regulatory role for this SUMOylation-modulated phosphorylation.

引用

页码：27342 / 27349

页数：8

共 26 条

[1]

A multidimensional chromatography technology for in-depth phosphoproteome analysis [J].

Albuquerque, Claudio P. ;

Smolka, Marcus B. ;

Payne, Samuel H. ;

Bafna, Vineet ;

Eng, Jimmy ;

Zhou, Huilin .

MOLECULAR & CELLULAR PROTEOMICS, 2008, 7 (07) :1389-1396

[2]

Regulation of protein tyrosine phosphatase 1B by sumoylation [J].

Dadke, Shrikrishna ;

Cotteret, Sophie ;

Yip, Shu-Chin ;

Jaffer, Zahara M. ;

Haj, Fawaz ;

Ivanov, Alexey ;

Rauscher, Frank, III ;

Shuai, Ke ;

Ng, Tony ;

Neel, Benjamin G. ;

Chernoff, Jonathan .

NATURE CELL BIOLOGY, 2007, 9 (01) :80-U102

[3]

A proteomic strategy for gaining insights into protein sumoylation in yeast [J].

Denison, C ;

Rudner, AD ;

Gerber, SA ;

Bakalarski, CE ;

Moazed, D ;

Gygi, SP .

MOLECULAR & CELLULAR PROTEOMICS, 2005, 4 (03) :246-254

[4]

Ginkgolic Acid Inhibits Protein SUMOylation by Blocking Formation of the E1-SUMO Intermediate [J].

Fukuda, Isao ;

Ito, Akihiro ;

Hirai, Go ;

Nishimura, Shinichi ;

Kawasaki, Hisashi ;

Saitoh, Hisato ;

Kimura, Ken-ichi ;

Sodeoka, Mikiko ;

Yoshida, Minoru .

CHEMISTRY & BIOLOGY, 2009, 16 (02) :133-140

[5]

System-Wide Changes to SUMO Modifications in Response to Heat Shock [J].

Golebiowski, Filip ;

Matic, Ivan ;

Tatham, Michael H. ;

Cole, Christian ;

Yin, Yili ;

Nakamura, Akihiro ;

Cox, Juergen ;

Barton, Geoffrey J. ;

Mann, Matthias ;

Hay, Ronald T. .

SCIENCE SIGNALING, 2009, 2 (72) :ra24

[6]

Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1 [J].

Hietakangas, V ;

Ahlskog, JK ;

Jakobsson, AM ;

Hellesuo, M ;

Sahlberg, NM ;

Holmberg, CI ;

Mikhailov, A ;

Palvimo, JJ ;

Pirkkala, L ;

Sistonen, L .

MOLECULAR AND CELLULAR BIOLOGY, 2003, 23 (08) :2953-2968

[7]

PDSM, a motif for phosphorylation-dependent SUMO modification [J].

Hietakangas, V ;

Anckar, J ;

Blomster, HA ;

Fujimoto, M ;

Palvimo, JJ ;

Nakai, A ;

Sistonen, L .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (01) :45-50

[8]

PIAS1-mediated sumoylation of focal adhesion kinase activates its autophosphorylation [J].

Kadaré, G ;

Toutant, M ;

Formstecher, E ;

Corvol, JC ;

Carnaud, M ;

Boutterin, MC ;

Girault, JA .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (48) :47434-47440

[9]

Simultaneous determination of thiamphenicol, florfenicol and florfenicol amine in swine muscle by liquid chromatography-tandem mass spectrometry with immunoaffinity chromatography clean-up [J].

Luo, Pengjie ;

Chen, Xia ;

Liang, Chunlai ;

Kuang, Hua ;

Lu, Liming ;

Jiang, Zhigang ;

Wang, Zhanhui ;

Li, Cun ;

Zhang, Suxia ;

Shen, Jianzhong .

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2010, 878 (02) :207-212

[10]

Global Map of SUMO Function Revealed by Protein-Protein Interaction and Genetic Networks [J].

Makhnevych, Taras ;

Sydorskyy, Yaroslav ;

Xin, Xiaofeng ;

Srikumar, Tharan ;

Vizeacoumar, Franco J. ;

Jerarn, Stanley M. ;

Li, Zhijian ;

Bahr, Sondra ;

Andrews, Brenda J. ;

Boone, Charles ;

Raught, Brian .

MOLECULAR CELL, 2009, 33 (01) :124-135

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