In vivo detection of scrapie cases from blood by infrared spectroscopy

被引：7

作者：

Carmona, P

Monzón, M

Monleón, E

Badiola, JJ

Monreal, J

机构：

[1] CSIC, Inst Estructura Mat, E-28006 Madrid, Spain

[2] Univ Zaragoza, Ctr Nacl Ref EET, Zaragoza, Spain

[3] CSIC, Inst Neurobiol Santiago Ramon & Cajal, E-28006 Madrid, Spain

来源：

JOURNAL OF GENERAL VIROLOGY | 2005年 / 86卷

关键词：

D O I：

10.1099/vir.0.81097-0

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

In the present study, infrared spectroscopy was shown to be able to distinguish healthy and scrapie-infected animals by analysis of the white-cell membranous fraction from blood. Infrared spectroscopy was able to detect not only clinical cases, but also animals at a preclinical stage of the disease. These findings suggest this technique as an accurate in vivo diagnostic tool that could be applied to animal as well as human samples. In addition to possibly avoiding the slaughter of a huge number of animals with the socio-economic consequences that this poses, the test could be expected to become useful in the prevention of human transmission by blood transfusion.

引用

收藏

页码：3425 / 3431

页数：7

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