Easier threading through web-based comparisons and cross-validations

被引：74

作者：

Douguet, D ^{[1
]}

Labesse, G ^{[1
]}

机构：

[1] Univ Montpellier I, Ctr Biochim Struct, CNRS, UMR5048,INSERM,U554, F-34060 Montpellier, France

来源：

BIOINFORMATICS | 2001年 / 17卷 / 08期

关键词：

D O I：

10.1093/bioinformatics/17.8.752

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We have developed a WWW server for the integration and comparison of protein structure predictions performed by five different servers. Users submit an amino acid sequence to a selected set of these prediction methods. Results are gathered on a web-based page in order to facilitate comparison and analysis. All the alignments are further evaluated through a common threading tool making their comparisons easier.

引用

页码：752 / 753

页数：2

共 11 条

[1] AN EMPIRICAL ENERGY FUNCTION FOR THREADING PROTEIN-SEQUENCE THROUGH THE FOLDING MOTIF [J].

BRYANT, SH ;

LAWRENCE, CE .

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 1993, 16 (01) :92-112

[2] LiveBench-1: Continuous benchmarking of protein structure prediction servers [J].

Bujnicki, JM ;

Elofsson, A ;

Fischer, D ;

Rychlewski, L .

PROTEIN SCIENCE, 2001, 10 (02) :352-361

[3] JPred: a consensus secondary structure prediction server [J].

Cuff, JA ;

Clamp, ME ;

Siddiqui, AS ;

Finlay, M ;

Barton, GJ .

BIOINFORMATICS, 1998, 14 (10) :892-893

[4] HAH1 is a copper-binding protein with distinct amino acid residues mediating copper homeostasis and antioxidant defense [J].

Hung, IH ;

Casareno, RLB ;

Labesse, G ;

Mathews, FS ;

Gitlin, JD .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (03) :1749-1754

[5] GenTHREADER: An efficient and reliable protein fold recognition method for genomic sequences [J].

Jones, DT .

JOURNAL OF MOLECULAR BIOLOGY, 1999, 287 (04) :797-815

[6] Enhanced genome annotation using structural profiles in the program 3D-PSSM [J].

Kelley, LA ;

MacCallum, RM ;

Sternberg, MJE .

JOURNAL OF MOLECULAR BIOLOGY, 2000, 299 (02) :499-520

[7] Incremental threading optimization (TITO) to help alignment and modelling of remote homologues [J].

Labesse, G ;

Mornon, JP .

BIOINFORMATICS, 1998, 14 (02) :206-211

[8] HOMSTRAD: A database of protein structure alignments for homologous families [J].

Mizuguchi, K ;

Deane, CM ;

Blundell, TL ;

Overington, JP .

PROTEIN SCIENCE, 1998, 7 (11) :2469-2471

[9] A platform for integrating threading results with protein family analyses [J].

Pazos, F ;

Rost, B ;

Valencia, A .

BIOINFORMATICS, 1999, 15 (12) :1062-1063

[10] Bridging the protein sequence-structure gap by structure predictions [J].

Rost, B ;

Sander, C .

ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE, 1996, 25 :113-136

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