The impact of sex and sex hormones on lung physiology and disease: lessons from animal studies

被引：165

作者：

Carey, Michelle A. ^{[1
]}

Card, Jeffrey W. ^{[1
]}

Voltz, James W. ^{[1
]}

Germolec, Dori R. ^{[1
]}

Korach, Kenneth S. ^{[1
]}

Zeldin, Darryl C. ^{[1
]}

机构：

[1] NIEHS, NIH, Res Triangle Pk, NC 27709 USA

来源：

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY | 2007年 / 293卷 / 02期

关键词：

estrogen; androgen; pulmonary;

D O I：

10.1152/ajplung.00174.2007

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Numerous animal studies have revealed significant effects of sex and sex hormones on normal lung development, lung physiology, and various lung diseases. The primary goal of this review is to summarize knowledge to date on the effects of sex and sex hormones on lung development, physiology, and disease in animals. Specific emphasis will be placed on fibrosis, allergic airway disease, acute lung injury models, respiratory infection, and lung toxicology studies.

引用

收藏

页码：L272 / L278

页数：7

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