Regioselective addition of the prenal potassium dienolate onto α,β-unsaturated aldehydes.: A short access to polyenaldehydes.

被引：16

作者：

Cahard, D ^{[1
]}

Poirier, JM

Duhamel, P

机构：

[1] Univ Rouen, UPRES A 6014, F-76821 Mt St Aignan, France

[2] Inst Rech Chim Organ Fine, F-76821 Mt St Aignan, France

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 39期

关键词：

D O I：

10.1016/S0040-4039(98)01544-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The potassium dienolate of prenal obtained by treatment of the corresponding dienoxysilane with tBuOK was reacted with enaldehydes. In all cases a gamma-specific reaction occurs. According to the reaction conditions gamma;1,2 or a gamma;1,4 coupled product was selectively obtained with enals. The gamma;1,2 reaction provided an efficient prenylation procedure. A short two-step synthesis of retinal is described. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：7093 / 7096

页数：4

共 10 条

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