Nanosensors and biochips: frontiers in biomolecular diagnostics

被引:157
作者
Vo-Dinh, T [1 ]
Cullum, BM [1 ]
Stokes, DL [1 ]
机构
[1] Oak Ridge Natl Lab, Adv Monitoring Dev Grp, Oak Ridge, TN 37831 USA
关键词
index; nanosensor; biosensor; nanotechnology; biochip; microchip; benzopyrene tetrol; HIV; cancer;
D O I
10.1016/S0925-4005(00)00705-X
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
In the past two decades, the biotechnology and medical fields have seen great advances in the development of novel technologies that open new horizons for identifying and quantifying biomolecules, and diagnosing diseases. This manuscript provides an overview of two of those important technologies, nanosensors and biochips. We describe various types of nanosensors and biochips that have been developed for biological and medical applications, along with significant advances achieved over the last several years in these technologies. Some applications of nanosensors, developed in our laboratory for single-cell analysis, and applications of biochips for biological sensing of pathogenic agents and medical diagnostics are described to illustrate the usefulness and potential of these technologies. (C) 2001 Elsevier Science B.V. Ah rights reserved.
引用
收藏
页码:2 / 11
页数:10
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