Microarrays in brain research: the good, the bad and the ugly

被引:52
作者
Mirnics, K [1 ]
机构
[1] Univ Pittsburgh, Sch Med, Dept Psychiat, Pittsburgh, PA 15261 USA
关键词
D O I
10.1038/35077587
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Making sense of microarray data is a complex process, in which the interpretation of findings will depend on the overall experimental design and judgement of the investigator performing the analysis. As a result, differences in tissue harvesting, microarray types, sample labelling and data analysis procedures make post hoc sharing of microarray data a great challenge. To ensure rapid and meaningful data exchange, we need to create some order out of the existing chaos. In these ground-breaking microarray standardization and data sharing efforts, NIH agencies should take a leading role.
引用
收藏
页码:444 / 447
页数:4
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