The tubulin fraternity: alpha to eta

被引：158

作者：

Dutcher, SK ^{[1
]}

机构：

[1] Washington Univ, Sch Med, Dept Genet, St Louis, MO 63110 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 2001年 / 13卷 / 01期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0955-0674(00)00173-3

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Microtubules perform essential and diverse functions in eukaryotic cells. They are required for spindles during mitosis and meiosis, for axonal transport, for organelle positioning, and for cilia and flagella. gamma -tubulin is necesary to initiate the assembly of alpha-beta tubulin heterodimers into microtubule polymers. Recent genetic analyses and database searches have added four new members of the tubulin superfamily, which now includes alpha (-), beta (-), gamma (-), delta (-), epsilon (-), zeta (-), and eta (-)tubulin.

引用

页码：49 / 54

页数：6

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