An autoxidative approach to 1,2,3,4-tetrahydroisoquinolin-l-one and tetrahydro-β-carbolin-l-one

被引：9

作者：

Bois-Choussy, M ^{[1
]}

De Paolis, M ^{[1
]}

Zhu, JP ^{[1
]}

机构：

[1] CNRS, Inst Chim Subst Nat, F-91198 Gif Sur Yvette, France

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 20期

关键词：

D O I：

10.1016/S0040-4039(01)00482-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of N-benzyl 1,2,3,4-tetrahydroisoquinoline-1-carboxylate with sodium hydride in N,N-dimethylformamide gives the corresponding N-benzyl 1,2,3,4-tetrahydroisoquinolin-1-one in quantitative yield. The N-benzyl 1,2,3,4-tetrahydro-beta -carbolin-1-one is prepared in a similar fashion. The N-deprotection occurred concomitantly with the oxidative decarboxylation when the nitrogen was benzyloxycarbonylated. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：3427 / 3430

页数：4

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