Clinical review: Acid-base abnormalities in the intensive care unit

被引：79

作者：

Kaplan, LJ ^{[1
]}

Frangos, S ^{[1
]}

机构：

[1] Yale Univ, Sch Med, Dept Surg, Sect Trauma Surg Crit Care & Surg Emergencies, New Haven, CT 06510 USA

来源：

CRITICAL CARE | 2005年 / 9卷 / 02期

关键词：

D O I：

10.1188/cc2912

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Acid-base abnormalities are common in the critically ill. The traditional classification of acid-base abnormalities and a modern physico-chemical method of categorizing them will be explored. Specific disorders relating to mortality prediction in the intensive care unit are examined in detail. Lactic acidosis, base excess, and a strong ion gap are highlighted as markers for increased risk of death.

引用

收藏

页码：198 / 203

页数：6

相关论文

共 48 条

[1] LACTATE CLEARANCE AND SURVIVAL FOLLOWING INJURY [J].

ABRAMSON, D ;

SCALEA, TM ;

HITCHCOCK, R ;

TROOSKIN, SZ ;

HENRY, SM ;

GREENSPAN, J .

JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 1993, 35 (04) :584-589

[2] Unmeasured anions identified by the Fencl-Stewart method predict mortality better than base excess, anion gap, and lactate in patients in the pediatric intensive care unit [J].

Balasubramanyan, N ;

Havens, PL ;

Hoffman, GM .

CRITICAL CARE MEDICINE, 1999, 27 (08) :1577-1581

[3] Utility of illness severity scoring for prediction of prolonged surgical critical care [J].

Barie, PS ;

Hydo, LJ ;

Fischer, E .

JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 1996, 40 (04) :513-519

[4] The golden hour and the silver day: Detection and correction of occult hypoperfusion within 24 hours improves outcome from major trauma [J].

Blow, O ;

Magliore, L ;

Claridge, JA ;

Butler, K ;

Young, JS .

JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 1999, 47 (05) :964-969

[5] Base deficit does not predict mortality when secondary to hyperchloremic acidosis [J].

Brill, SA ;

Stewart, TR ;

Brundage, SI ;

Schreiber, MA .

SHOCK, 2002, 17 (06) :459-462

[6] Persistent occult hypoperfusion is associated with a significant increase in infection rate and mortality in major trauma patients [J].

Claridge, JA ;

Crabtree, TD ;

Pelletier, SJ ;

Butler, K ;

Sawyer, RG ;

Young, JS .

JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 2000, 48 (01) :8-14

[7] The strong ion gap does not have prognostic value in critically ill patients in a mixed medical/surgical adult ICU [J].

Cusack, RJ ;

Rhodes, A ;

Lochhead, P ;

Jordan, B ;

Perry, S ;

Ball, JAS ;

Grounds, RM ;

Bennett, ED .

INTENSIVE CARE MEDICINE, 2002, 28 (07) :864-869

[8] Admission base deficit predicts transfusion requirements and risk of complications [J].

Davis, JW ;

Parks, SN ;

Kaups, KL ;

Gladen, HE ;

ODonnellNicol, S .

JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 1996, 41 (05) :769-774

[9] Base deficit is superior to pH in evaluating clearance of acidosis after traumatic shock [J].

Davis, JW ;

Kaups, KL ;

Parks, SN .

JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 1998, 44 (01) :114-118

[10] Diagnosis of metabolic acid-base disturbances in critically ill patients [J].

Fencl, V ;

Jabor, A ;

Kazda, A ;

Figge, J .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2000, 162 (06) :2246-2251

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