Olefin cross-metathesis reactions at room temperature using the nonionic amphiphile "PTS": Just add water

被引：137

作者：

Lipshutz, Bruce H. ^{[1
]}

Aguinaldo, Grant T. ^{[1
]}

Ghorai, Subir ^{[1
]}

Voigtritter, Karl ^{[1
]}

机构：

[1] Univ Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA

来源：

ORGANIC LETTERS | 2008年 / 10卷 / 07期

关键词：

D O I：

10.1021/ol800028x

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first examples of unsymmetrical olefin cross-metathesis reactions in water, involving water-insoluble substrates, at room temperature and using commercially available catalysts are reported. The key to success is to include small percentages of the nonionic, vitamin E-based amphiphile "PTS". The nanometer micelles formed accommodate water-insoluble substrates, along with a readily available Ru-based metathesis catalyst. Reactions proceed at ambient temperatures with high efficiency and very high E-selectivity, and products are easily isolated.

引用

页码：1325 / 1328

页数：4

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