Innovation - Ibis T5000: a universal biosensor approach for microbiology

被引：226

作者：

Ecker, David J. ^{[1
]}

Sampath, Rangarajan ^{[1
]}

Massire, Christian ^{[1
]}

Blyn, Lawrence B. ^{[1
]}

Hall, Thomas A. ^{[1
]}

Eshoo, Mark W. ^{[1
]}

Hofstadler, Steven A. ^{[1
]}

机构：

[1] Ibis Biosci, Carlsbad, CA 92008 USA

来源：

NATURE REVIEWS MICROBIOLOGY | 2008年 / 6卷 / 07期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1038/nrmicro1918

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We describe a new technology, the Ibis T5000, for the identification of pathogens in clinical and environmental samples. The Ibis T5000 couples nucleic acid amplification to high-performance electrospray ionization mass spectrometry and base-composition analysis. The system enables the identification and quantification of a broad set of pathogens, including all known bacteria, all major groups of pathogenic fungi and the major families of viruses that cause disease in humans and animals, along with the detection of virulence factors and antibiotic resistance markers.

引用

页码：553 / 558

页数：6

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