A novel arsenical in clam kidney identified by liquid chromatography/electrospray ionisation mass spectrometry

被引：32

作者：

Francesconi, KA

Edmonds, JS

机构：

[1] Univ So Denmark, Inst Ecol, DK-5230 Odense, Denmark

[2] Natl Inst Environm Studies, Endocrine Disrupter Res Lab, Tsukuba, Ibaraki 3050053, Japan

来源：

RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 2001年 / 15卷 / 17期

关键词：

D O I：

10.1002/rcm.420

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Kidneys of clams of the genus Tridacna accumulate metabolic products from symbiotic unicellular algae that grow in the mantles of the clams. These metabolites include organoarsenic compounds that are biosynthesised by algae from arsenate in seawater. The arsenic compounds in aqueous extracts of the kidney of the giant clam T. derasa were investigated by liquid chromatography/electrospray ionisation mass spectrometry. About 50% of the water-soluble arsenic was present as dimethylarsinoylribosides and dimethylarsinate which are common algal metabolites. The major compound in the kidney (50% of water-soluble arsenic) was identified as a 5-dimethylarsinoyl-2,3,4-trihydroxycarboxylic acid, a new natural product. Copyright (C) 2001 John Wiley & Sons, Ltd.

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页码：1641 / 1646

页数：6

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