Ginsenoside Rg(5), a genuine dammarane glycoside from Korean red ginseng

被引：59

作者：

Kim, SI

Park, JH

Ryu, JH

Park, JD

Lee, YH

Park, JH

Kim, TH

Kim, JM

Baek, NI

机构：

[1] SEOUL NATL UNIV,COLL PHARM,SEOUL 151742,SOUTH KOREA

[2] SOOKMYUNG WOMENS UNIV,DEPT PHARM,SEOUL 140742,SOUTH KOREA

来源：

ARCHIVES OF PHARMACAL RESEARCH | 1996年 / 19卷 / 06期

关键词：

Panax ginseng; red ginseng; novel saponin; ginsenoside Rg(5); stereostructure; NMR data;

D O I：

10.1007/BF02986026

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A genuine dammarane glycoside, named ginsenoside Rg,, has been isolated by repeated column chromatography and preparative HPLC from the MeOH extract of Korean red ginseng (Panax ginseng C.A. Meyer). The chemical structure of ginsenoside Rg(5) was determined as 3-O-[beta-D-glucopyranosyl (1-->2)-beta-D-glucopyranosyl] dammar-20(22),24-diene-3 beta,12 beta-diol by spectral and chemical methods. The stereostructure of a double bond at C-20(22) of ginsenoside Rg, was characterized as (E) from the chemical shift of C-21 in the C-13-NMR and a NOESY experiment in the H-1-NMR.

引用

页码：551 / 553

页数：3