Recovery of swallowing function is accompanied by the expansion of the cortical map

被引：23

作者：

Oh, Byung-Mo

Kim, Dae-Yul

Paik, Nam-Jong

机构：

[1] Seoul Natl Univ Bundang Hosp, Seoul Natl Univ Coll Med, Dept Rehabil Med, Songnam 463707, South Korea

[2] Gangwon Do Rehab Hosp, Dept Rehabil Med, Chunchon, South Korea

[3] Univ Ulsan, Coll Med, Seoul Asan Med Ctr, Dept Rehabil Med, Seoul, South Korea

来源：

INTERNATIONAL JOURNAL OF NEUROSCIENCE | 2007年 / 117卷 / 09期

基金：

新加坡国家研究基金会;

关键词：

cortex reorganization; dysphagia; electrical stimulation; swallowing;

D O I：

10.1080/00207450600936254

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

To determine whether multiple sessions of electrical stimulation (ES) applied to neck muscles improve swallowing function and whether this improvement is accompanied by cortical reorganization in patients with dysphagia, before-after trials were performed on eight subjects. ES was applied for 1 hour, 5 days a week for 2 weeks. Swallowing function significantly improved after 2 weeks of ES, and this change was found to correlate with cortical reorganization measured by corticobulbar output maps. This study suggests that multiple sessions of ES applied to the neck muscles improve swallowing function via a mechanism involving long-term cortical reorganization.

引用

收藏

页码：1215 / 1227

页数：13

相关论文

共 19 条

[1] Neurophysiology of swallowing [J].

Ertekin, C ;

Aydogdu, I .

CLINICAL NEUROPHYSIOLOGY, 2003, 114 (12) :2226-2244

[2] Driving plasticity in human adult motor cortex is associated with improved motor function after brain injury [J].

Fraser, C ;

Power, M ;

Hamdy, S ;

Rothwell, J ;

Hobday, D ;

Hollander, I ;

Tyrell, P ;

Hobson, A ;

Williams, S ;

Thompson, D .

NEURON, 2002, 34 (05) :831-840

[3]

Freed M L, 2001, Respir Care, V46, P466

[4] Recovery of swallowing after dysphagic stroke relates to functional reorganization in the intact motor cortex [J].

Hamdy, S ;

Aziz, Q ;

Rothwell, JC ;

Power, M ;

Singh, KD ;

Nicholson, DA ;

Tallis, RC ;

Thompson, DG .

GASTROENTEROLOGY, 1998, 115 (05) :1104-1112

[5] Long-term reorganization of human motor cortex driven by short-term sensory stimulation [J].

Hamdy, S ;

Rothwell, JC ;

Aziz, Q ;

Singh, KD ;

Thompson, DG .

NATURE NEUROSCIENCE, 1998, 1 (01) :64-68

[6] Modulation of human corticomotor excitability by somatosensory input [J].

Kaelin-Lang, A ;

Luft, AR ;

Sawaki, L ;

Burstein, AH ;

Sohn, YH ;

Cohen, LG .

JOURNAL OF PHYSIOLOGY-LONDON, 2002, 540 (02) :623-633

[7] Cortical motor reorganization following early brain damage and hemispherectomy demonstrated by transcranial magnetic stimulation [J].

Kastrup, O ;

Leonhardt, G ;

Kurthen, M ;

Hufnagel, A .

CLINICAL NEUROPHYSIOLOGY, 2000, 111 (08) :1346-1352

[8] Electrical stimulation driving functional improvements and cortical changes in subjects with stroke [J].

Kimberley, TJ ;

Lewis, SM ;

Auerbach, EJ ;

Dorsey, LL ;

Lojovich, JM ;

Carey, JR .

EXPERIMENTAL BRAIN RESEARCH, 2004, 154 (04) :450-460

[9] Synchronized electrical stimulation in treating pharyngeal dysphagia [J].

Leelamanit, V ;

Limsakul, C ;

Geater, A .

LARYNGOSCOPE, 2002, 112 (12) :2204-2210

[10] Treatment-induced cortical reorganization after stroke in humans [J].

Liepert, J ;

Bauder, H ;

Miltner, WHR ;

Taub, E ;

Weiller, C .

STROKE, 2000, 31 (06) :1210-1216