Concentrations of airborne Aspergillus compared to the incidence of invasive aspergillosis: lack of correlation

被引:77
作者
Hospenthal, DR
Kwon-Chung, KJ
Bennett, JE
机构
[1] NIAID, Clin Mycol Sect, LCI, NIH, Bethesda, MD 20892 USA
[2] Walter Reed Army Med Ctr, Infect Dis Serv, Washington, DC 20307 USA
关键词
Aspergillus; aspergillosis; epidemiology; nosocomial;
D O I
10.1046/j.1365-280X.1998.00147.x
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Air sampling of the rooms and corridors of the oncology wards of the hospital was carried out over a 54-week period to assess the concentration of viable Aspergillus conidia. A. fumigatus and A. flavus were recovered at a mean of 1.83 cfu m(-3) air sampled. Individual samplings yielded concentrations of up to 11.6 cfu m(-3). Other Aspergillus spp. were recovered at a mean of 2.38 cfu m(-3) (maximum 32.6 cfu m(-3)). Concentration was not correlated with season or hospital ward. Review of autopsy results showed an average of 6.6 cases of aspergillosis annually over a 22-year period. No seasonal variation in case incidence was found. Six cases of invasive aspergillosis were diagnosed on the three cancer wards during the air-sampling period, but no association was seen linking these cases with changes in recovery of airborne Aspergillus. A seasonal pattern was not observed in the overall incidence of aspergillosis cases nor concentrations of airborne conidia.
引用
收藏
页码:165 / 168
页数:4
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