Electrochemical biosensing of DNA hybridization by electroactive ferrocene functionalized polypyrrole

被引：21

作者：

Korri-Youssoufi, H ^{[1
]}

Makrouf, B ^{[1
]}

机构：

[1] Inst Chim Mol Orsay, Lab Chim Bioorgan & Bioinorgan, F-91600 Orsay, France

来源：

SYNTHETIC METALS | 2001年 / 119卷 / 1-3期

关键词：

polypyrrole; Ferrocene; electrochemical biosensors; DNA hybridization;

D O I：

10.1016/S0379-6779(00)01509-5

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Herein we report biosensing hybridization of DNA based on the electrochemical response of ferrocenyl groups grafted to polypyrrole. The synthesis of precursor polymer and its electrochemical properties was demonstrated. We show that the sensitivity of DNA hybridization was evaluated to picomolar.

引用

页码：265 / 266

页数：2

共 7 条

[1] Direct chemical functionalization of as-grown electroactive polypyrrole film containing leaving groups
Godillot, P
KorriYoussoufi, H
Srivastava, P
ElKassmi, A
Garnier, F
[J]. SYNTHETIC METALS, 1996, 83 (02) : 117 - 123
[2] KORRIYOUSSOUFI H, 1997, J AM CHEM SOC, V119, P7389
[3] PREPARATION OF A DNA MATRIX VIA AN ELECTROCHEMICALLY DIRECTED COPOLYMERIZATION OF PYRROLE AND OLIGONUCLEOTIDES BEARING A PYRROLE GROUP
LIVACHE, T
ROGET, A
DEJEAN, E
BARTHET, C
BIDAN, G
TEOULE, R
[J]. NUCLEIC ACIDS RESEARCH, 1994, 22 (15) : 2915 - 2921
[4] Mikkelsen Susan R., 1996, Electroanalysis, V8, P15, DOI 10.1002/elan.1140080104
[5] CONFORMATIONAL TRANSITIONS OF NUCLEIC-ACIDS STUDIED BY IR AND RAMAN SPECTROSCOPIES
TAILLANDIER, E
LIQUIER, J
GHOMI, M
[J]. JOURNAL OF MOLECULAR STRUCTURE, 1989, 214 : 185 - 211
[6] VANNESS J, 1991, NUCLEIC ACIDS RES, V19, P3345
[7] Instant DNA detection
Wilson, EK
[J]. CHEMICAL & ENGINEERING NEWS, 1998, 76 (21) : 47 - 49

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